Infectious food poisoning is a very common, unpleasant and dangerous disease that can happen anywhere, including the workplace. The most common causes of infectious food poisoning are bacteria and viruses, but there are also other types of pathogens such as primitive parasitic animals and toxins with plant or animal origin. In this final paper, the incidence of infectious food poisoning at the workplace in the Republic of Croatia from 2009 to 2019 was investigated. A retrospective analysis of the prospective database was performed (annual reports on reported injuries at work, which are available on the website of the Croatian Institute for Public Insurance under the Occupational Medicine branch). With this aim, data on work injuries caused by poisoning and infections, the action of living organisms and injuries involving diseases of the digestive system were statistically processed. Sectors of activity in which hygienic working conditions are lower, record more cases of infectious food poisoning. The key of prediction and prevention is in the engagement of management and all employees in improving hygienic conditions at the workplace.