The public fire brigade of the City of Trogir in cooperation with the Conservation Department in Trogir are implementing a program called "Reducing the risk of fire in the historic city of Trogir". The goal of the project is to propose specific measures that will result in reducing the risk of fire, both for the historical city of Trogir and for other fire-endangered parts of the cultural heritage area in the Republic of Croatia. In the introductory part of work, it is presented what the ICCROM project is, and the PREVENT program too, which refers to the fire risk of historical cultural heritage. The project itself is significant in that it accurately defines response protocols in the event of a major incident and threat to cultural heritage due to IV fire. The continuation of the work shows the way in which the project was specified and narrowly presented on the example of the City of Trogir, i.e. the very application of the Prevent project to the Sacred Art Collection of the Parish of St. Lawrence in Trogir. The project extensively shows the response plan and the rescue of valuable historical art in case of fire. It is very important that projects of this type are presented to all actors who actively or passively participate in the preservation of historical cultural heritage in the Republic of Croatia.